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Article

Artificial Intelligence-Powered Spatial Analysis of Immune Phenotypes in Resected Pancreatic Cancer.

JAMA surgery - 1 Aug 2025

Kim Hyemin, Choi Jin Ho, Lim Yoojoo, Yoon So Jeong, Jang Kee-Taek, Ock Chan-Young, Choi Young Hoon, Joe Cheolyong, Song Sanghoon, Moon Jimin, Song Heon, Pereira Sergio, Lee Seungeun, Park Sujin, Kim Kyunga, Lee Se-Hoon, Kim Hongbeom, Shin Sang Hyun, Heo Jin Seok, Lee Kwang Hyuck, Lee Kyu Taek, Lee Jong Kyun, Han In Woong, Park Joo Kyung

Abstract excerpt

Importance: Although tumor-infiltrating lymphocytes (TILs) have been implicated as prognostic biomarkers across various malignancies, the clinical application remains challenging. This study evaluated the applicability of artificial intelligence (AI)-powered spatial mapping of TIL density for prognostic assessment in resected pancreatic ductal adenocarcinoma (PDAC). Objective: To evaluate the prognostic...

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Identifiers

PMID: 40560550
DOI: 10.1001/jamasurg.2025.1999
PMCID: PMC12199178

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