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Article

Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma.

Frontiers in immunology - 1 Jan 2020

Lundgren Sebastian, Micke Patrick, Elebro Jacob, Heby Margareta, Hrynchyk Ina, Nodin Björn, Leandersson Karin, Mezheyeuski Artur, Jirström Karin

Abstract excerpt

Background: The clinical management of pancreatic and other periampullary neoplasms remains challenging. In contrast to other cancer types, immunotherapies are largely ineffective, and the reason for the deprived immune response and the immune inhibiting cellular composition is only fragmentarily understood. The aim of this study was to comprehensively map the abundance, topographic distribution and spatial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33013928
DOI: 10.3389/fimmu.2020.558169
PMCID: PMC7511775

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