Article

Donor-reactive T cells and innate immune cells promote pig-to-human decedent xenograft rejection

2025-04-22

Abstract excerpt

<title>Abstract</title> <p>Xenotransplantation of pig organs is a promising solution to the organ shortage; however, rejection remains a major obstacle. Pig-to-human decedent transplantation provides an opportunity to study immune barriers to xenotransplantation experimentally. We tracked donor-reactive T cell dynamics in a 61-day pig-to-human decedent thymokidney xenotransplant. Xenogeneic donor-reactive T cell...

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Literature Corpus work: 7382794d-f199-530a-874e-114cef2b4958
DOI: 10.21203/rs.3.rs-6474835/v1

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