Back to search

Article

Biologically informed instrument selection for dietary Mendelian randomization using chemosensory receptor variants

2026-02-06

Abstract excerpt

<h4>Background</h4> Mendelian randomization (MR) is increasingly used for causal inference in nutritional epidemiology; however, dietary MR studies often rely on instruments statistically selected from genome-wide association studies of self-reported intake, which are vulnerable to pleiotropy and reverse causation and may violate core MR assumptions. We aimed to develop and evaluate a biologically informed framew...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f207d21e-bed1-5166-953a-d60241949ad2
DOI
10.64898/2026.02.05.26345702
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Biologically informed instrument selection for dietary Mendelian randomization using chemosensory receptor variantsDOI 10.64898/2026.02.05.26345702
A biologically informed framework for instrument selection in dietary Mendelian randomization using chemosensory genetics.Semantic proximity
Comparing genome-wide significant and chemosensory variants as instruments for dietary patterns in Mendelian randomisationSemantic proximity
Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic loci and establishes causal relationships between educational attainment and healthy eatingSemantic proximity
Dietary Intake Mendelian Randomization: Assessment and Development of Methods for Instrument Selection and Robust InferenceSemantic proximity
Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.Semantic proximity
Genetic Variants Influencing Taste Perception and Food Preferences: Current Evidence.Semantic proximity
Associations Between Genetic Variants of the Taste Receptors, TAS1R2, TAS1R3, TAS2R38, and CD36 and Human LongevitySemantic proximity
Sweet Taste Receptors’ Genetic Variability in Advanced Potential Targets of ObesitySemantic proximity
Understanding the Determinants of Sweet Liking in the African and East Asian Ancestry Groups in the U.S. – A Study ProtocolSemantic proximity
Missense genetic variants in major bitter taste receptors are associated with diet quality and food intake in a highly admixed underrepresented population.Semantic proximity
Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.-A study protocol.Semantic proximity
Exploring genetic modifiers influencing adult eating behaviour: A scoping review.Semantic proximity
Select a neighboring publication to make it the new centre.