Article

Dietary Intake Mendelian Randomization: Assessment and Development of Methods for Instrument Selection and Robust Inference

2025-06-27

Abstract excerpt

<h4>Background</h4> Mendelian randomization (MR) uses genetic instruments (GI) to infer causality between exposures, like dietary intake, and health outcomes. Almost all MR of dietary intake use the full set of genome-wide significant (GWS) variants in the GI, and therefore, causal estimates are likely biased by variants that act indirectly on diet. <h4>Objective</h4> First, we performed an assessment of the die...

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Literature Corpus work: 2f141d7a-21b6-55a3-9f8e-7ef47662f3cb
DOI: 10.1101/2025.06.26.25330002

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