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Article

Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.

Nature communications - 19 Mar 2020

Cole Joanne B, Florez Jose C, Hirschhorn Joel N

Abstract excerpt

Unhealthful dietary habits are leading risk factors for life-altering diseases and mortality. Large-scale biobanks now enable genetic analysis of traits with modest heritability, such as diet. We perform a genomewide association on 85 single food intake and 85 principal component-derived dietary patterns from food frequency questionnaires in UK Biobank. We identify 814 associated loci, including olfactory...

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Biological Specimen Banks
Eating
Feeding Behavior
Inheritance Patterns
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Principal Component Analysis

Receptors, Odorant

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PMID: 32193382
DOI: 10.1038/s41467-020-15193-0
PMCID: PMC7081342

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