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Protective pan-betacoronavirus neutralizing antibodies by vaccination

2026-08-07

Abstract excerpt

<h4>ABSTRACT</h4> The continued emergence of betacoronaviruses underscores the urgent need for vaccines that provide broadly protective immunity. Here, we present an epitope-focused vaccine strategy targeting the conserved S2 stem-helix region of the spike fusion machinery, a broadly neutralizing antibody-(bnAb) epitope shared across betacoronaviruses yet partially occluded on the native spike. Immunization of no...

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Identifiers and source

Literature Corpus work
f1ec1551-9233-5cae-a614-3b38636294f5
DOI
10.64898/2026.08.06.743418
Open publication

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Protective pan-betacoronavirus neutralizing antibodies by vaccinationDOI 10.64898/2026.08.06.743418
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