Article

Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates

2023-12-19

Abstract excerpt

<h4>ABSTRACT</h4> Immunization with mRNA or viral vectors encoding spike with diproline substitutions (S-2P) has provided protective immunity against severe COVID-19 disease. How immunization with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike elicits neutralizing antibodies (nAbs) against difficult-to-neutralize variants of concern (VOCs) remains an area of great interest. Here, we compare im...

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Literature Corpus work: 709e2cf2-ce94-5ed8-b28c-4b9cd3e5457c
DOI: 10.1101/2023.12.18.572191

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