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A Spike Trimer Dimer-Inducing Nanobody with Anti-Sarbecovirus Activity

2024-06-19

Abstract excerpt

The continued emergence and zoonotic threat posed by coronaviruses highlight the urgent need for effective antiviral strategies with broad reactivity to counter new emerging strains. Nanobodies (or single-domain antibodies) are promising alternatives to traditional monoclonal antibodies, due to their small size, cost-effectiveness and ease of bioengineering. Here, we describe 7F, a llama-derived nanobody, targetin...

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Identifiers and source

Literature Corpus work
ebbedb59-b1e0-55fa-b850-e6261a256782
DOI
10.1101/2024.06.19.598823
Open publication

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A Spike Trimer Dimer-Inducing Nanobody with Anti-Sarbecovirus ActivityDOI 10.1101/2024.06.19.598823
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