Article

Inferring demographic and selective histories from population genomic data using a two-step approach in species with coding-sparse genomes: an application to human data

2024-09-22

Abstract excerpt

The demographic history of a population, and the distribution of fitness effects (DFE) of newly arising mutations in functional genomic regions, are fundamental factors dictating both genetic variation and evolutionary trajectories. Although both demographic and DFE inference has been performed extensively in humans, these approaches have generally either been limited to simple demographic models involving a singl...

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Literature Corpus work: f1e48d5a-c763-59ef-8735-1f507bdf90aa
DOI: 10.1101/2024.09.19.613979

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