Article

Efficient inference of population size histories and locus-specific mutation rates from large-sample genomic variation data

2014-06-28

Abstract excerpt

With the recent increase in study sample sizes in human genetics, there has been growing interest in inferring historical population demography from genomic variation data. Here, we present an efficient inference method that can scale up to very large samples, with tens or hundreds of thousands of individuals. Specifically, by utilizing analytic results on the expected frequency spectrum under the coalescent and b...

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Literature Corpus work: 2cdfa43a-bd4a-58ad-82ef-702c421d3aed
DOI: 10.1101/006742

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