Article
Neutral genomic regions refine models of recent rapid human population growth.
Proceedings of the National Academy of Sciences of the United States of America - 14 Jan 2014
Gazave Elodie, Ma Li, Chang Diana, Coventry Alex, Gao Feng, Muzny Donna, Boerwinkle Eric, Gibbs Richard A, Sing Charles F, Clark Andrew G, Keinan Alon
Abstract excerpt
Human populations have experienced dramatic growth since the Neolithic revolution. Recent studies that sequenced a very large number of individuals observed an extreme excess of rare variants and provided clear evidence of recent rapid growth in effective population size, although estimates have varied greatly among studies. All these studies were based on protein-coding genes, in which variants are also impacted...
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