Article
Fine-scale recombination patterns differ between chimpanzees and humans.
Nature genetics - 1 Apr 2005
Ptak Susan E, Hinds David A, Koehler Kathrin, Nickel Birgit, Patil Nila, Ballinger Dennis G, Przeworski Molly, Frazer Kelly A, Pääbo Svante
Abstract excerpt
Recombination rates seem to vary extensively along the human genome. Pedigree analysis suggests that rates vary by an order of magnitude when measured at the megabase scale, and at a finer scale, sperm typing studies point to the existence of recombination hotspots. These are short regions (1-2 kb) in which recombination rates are 10-1,000 times higher than the background rate. Less is known about how...
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