Article

Disease and phenotype relevant genetic variants identified from histone acetylomes in human hearts

2019-01-31

Abstract excerpt

Identifying genetic markers for heterogeneous complex diseases such as heart failure has been challenging, and may require prohibitively large cohort sizes in genome-wide association studies (GWAS) in order to demonstrate statistical significance 1 . On the other hand, chromatin quantitative trait loci (QTL), elucidated by direct epigenetic profiling of specific human tissues, may contribute towards prioritising...

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Literature Corpus work: f1d1151c-a3bc-5e4f-a56d-b53dda0e8c7c
DOI: 10.1101/536763

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