Article

<i>ERBB4</i>Mutant Alleles Found in<i>BRAF</i>WT Melanomas That Drive the Proliferation of a<i>BRAF</i>WT Melanoma Cell Line

2022-06-23

Abstract excerpt

Metastatic skin cutaneous melanomas that contain wild-type BRAF alleles (“ BRAF WT melanomas”) remain a significant clinical challenge, primarily because of the paucity of targets for therapeutic intervention. In prior work, in silico analyses of The Cancer Genome Atlas Skin Cutaneous Melanoma (TCGA-SKCM) dataset suggested that elevated transcription of the gene that encodes the ERBB4 receptor tyrosine kinase may...

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Literature Corpus work: f1c96f3e-2b01-583f-b736-a497db9278d3
DOI: 10.1101/2022.06.21.22276707

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