Article
High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.
Melanoma research - 1 Jun 2015
van den Hurk Karin, Balint Balazs, Toomey Sinead, O'Leary Patrick C, Unwin Louise, Sheahan Kieran, McDermott Enda W, Murphy Ian, van den Oord Joost J, Rafferty Mairin, FitzGerald Dara M, Moran Julie, Cummins Robert, MacEneaney Owen, Kay Elaine W, O'Brien Cathal P, Finn Stephen P, Heffron Cynthia C B B, Murphy Michelle, Yela Ruben, Power Derek G, Regan Padraic J, McDermott Clodagh M, O'Keeffe Allan, Orosz Zsolt, Donnellan Paul P, Crown John P, Hennessy Bryan T, Gallagher William M
Abstract excerpt
Because of advances in targeted therapies, the clinical evaluation of cutaneous melanoma is increasingly based on a combination of traditional histopathology and molecular pathology. Therefore, it is necessary to expand our knowledge of the molecular events that accompany the development and progression of melanoma to optimize clinical management. The central objective of this study was to increase our knowledge...
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