Article

Functional and sensitivity profiling of the <i>KIT</i> Mutation Landscape in Melanoma

2026-02-20

Abstract excerpt

Melanoma in Asia presents a unique epidemiological profile, with a higher prevalence of acral and mucosal subtypes compared to Western populations. While KIT mutations are found in up to 15% of Asian melanoma cases, clinical outcomes with KIT inhibitors have been modest due to heterogeneous mutation profiles and a lack of specific patient selection criteria. This study characterizes the landscape of KIT mutation...

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Literature Corpus work: 32f52d1f-1a0c-5a27-a6d8-e3ceb54b7787
DOI: 10.64898/2026.02.18.706482

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