Article

Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage

2023-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Prdm12 is an epigenetic regulator expressed in developing and mature nociceptive neurons, playing a key role in their specification during neurogenesis and modulating pain sensation at adulthood. In vitro studies suggested that Prdm12 recruits the methyltransferase G9a through its zinc finger domains to regulate target gene expression, but how Prdm12 interacts with G9a and whether G9a plays a r...

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Literature Corpus work: f16f15c9-4e8e-5671-b914-3273c6fd2816
DOI: 10.1101/2023.09.15.557867

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