Article

piRNA loss unleashes episodic transposition bursts

2026-07-16

Abstract excerpt

<h4>ABSTRACT</h4> In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon expression results in actual transposition, and if so, which and how frequently transposons mobilize upon piRNA loss. Here, we developed a framework to track transposon copy accumulation across genera...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 69690eb3-ad79-57c7-96ff-f0922a274ff3
DOI: 10.64898/2026.07.11.737971

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

piRNA loss unleashes episodic transposition burstsDOI 10.64898/2026.07.11.737971Read

A <i>trans</i> -piRNA network and transcriptional antagonism shape piRNA cluster functionSemantic proximity Read

Lifestyles of <i>Gypsy</i> -family transposons shape their regulatory mechanismsSemantic proximity Read

Rapid evolution of piRNA-mediated silencing of an invading transposable element was driven by abundant de novo mutations.Semantic proximity Read

<i>Flamenco</i> plasticity tunes somatic piRNAs, rewiring host isoforms and opening a route to heritable transposon spreadSemantic proximity Read

Maelstrom Represses Canonical Polymerase II Transcription within Bi-Directional piRNA Clusters in <i>Drosophila melanogaster</i>Semantic proximity Read

Rapid evolution of piRNA clusters in the <i>Drosophila melanogaster</i> ovarySemantic proximity Read

Recurrent Gene Duplication Diversifies Genome Defense Repertoire in Drosophila.Semantic proximity Read

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in <i>D. melanogaster</i> male germlineSemantic proximity Read

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the <i>Drosophila</i> genusSemantic proximity Read

A Naïve RNA Sampling Core Enables Adaptive piRNA Specificity Against Transposable ElementsSemantic proximity Read

Rapid evolution of promoters from germline-specifically expressed genes including transposon silencing factorsSemantic proximity Read

Dynamics and impacts of transposable element proliferation during the <i>Drosophila nasuta</i> species group radiationSemantic proximity Read