Article

Systematic single-cell analysis reveals dynamic control of transposable element activity orchestrating the endothelial-to-hematopoietic transition

2023-06-21

Abstract excerpt

<h4>Background</h4> The endothelial-to-hematopoietic transition (EHT) process during definitive hematopoiesis in vertebrate is highly conserved. Stage-specific expression of transposable elements (TEs) has been detected during zebrafish EHT and may promote hematopoietic stem cell formation by activating inflammatory signaling. However, little is known about how TEs contribute to the EHT process in human and mouse...

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Literature Corpus work: 1865044b-4b1b-54bd-89c8-4b5352fe5d1e
DOI: 10.1101/2023.06.19.545461

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