Article

Spotiphy enables single-cell spatial whole transcriptomics across the entire section

2024-11-12

Abstract excerpt

Spatial transcriptomics (ST) has advanced our understanding of tissue regionalization by enabling the visualization of gene expression within whole tissue sections, but the approach remains dogged by the challenge of achieving single-cell resolution without sacrificing whole genome coverage. Here we present Spotiphy (Spot imager with pseudo single-cell resolution histology), a novel computational toolkit that tran...

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Literature Corpus work: f1130de8-6803-5077-b6c4-6bde6a4abb60
DOI: 10.1101/2024.11.11.623040

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