Open-ST: High-resolution spatial transcriptomics in 3D

Abstract excerpt

Spatial transcriptomics (ST) methods have been developed to unlock molecular mechanisms underlying tissue development, homeostasis, or disease. However, there is a need for easy-to-use, high-resolution, cost-efficient, and 3D-scalable methods. Here, we report Open-ST, a sequencing-based, open-source experimental and computational resource to address these challenges and to study the molecular organization of tissu...

Topics

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• Cell Image Analysis Techniques
• Cytomegalovirus and herpesvirus research
• Gene Expression Profiling
• Phenotype
• Single-cell and spatial transcriptomics
• Technology
• Transcriptome
• Transplantation: Methods and Outcomes

Identifiers and source

Literature Corpus work

fc3a7fd0-8da9-5cdd-8f4a-1a828f166278

DOI

10.1101/2023.12.22.572554