Article

SpatioCell: Deep Integration of Histology and Spatial Transcriptomics for Profiling the Cellular Microenvironment at Single-Cell Level

2025-04-12

Abstract excerpt

Spatial transcriptomics (ST) is a powerful assay to capture gene expression in tissue context. However, due to the limitation of resolution, most existing ST datasets remain at multicellular resolution which hinders comprehensive understanding of the spatial organization. We propose SpatioCell, a computational algorithm to automatically extract both cell type and expression information at single-cell resolution fr...

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Literature Corpus work: fab7094f-7166-5cff-bd59-e546b04fe233
DOI: 10.1101/2025.04.07.647590

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