Article

STCS: A Platform-Agnostic Framework for Cell-Level Reconstruction in Sequencing-Based Spatial Transcriptomics

2026-03-02

Abstract excerpt

Sequencing-based spatial transcriptomics technologies, including Visium HD and Stereo-seq, now enable transcriptome-wide profiling at subcellular resolution. However, these platforms generate measurements over spatially barcoded units rather than biologically segmented cells, creating a fundamental bottleneck for cell-centric analysis and interpretation. Robust recon-struction of coherent single-cell transcriptome...

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Literature Corpus work: 5fbbda04-4a55-53e3-b438-b712b386acf6
DOI: 10.64898/2026.02.26.708370

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