Article

Divergent Evolution in Bilateral Prostate Cancer: a Case Study

2024-08-23

Abstract excerpt

Multifocal prostate cancer is a prevalent phenomenon, with most cases remaining uncharacterized from a genomic perspective. A patient presented with bilateral prostate cancer. On systematic biopsy, two indistinguishable clinicopathologic lesions were detected. Whole-genome sequencing displayed somatically unrelated tumours with distinct driver CNA regions, suggesting independent origins of the two tumors. We demon...

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Literature Corpus work: f10a2daf-e7b8-5f25-8a95-84c301903af5
DOI: 10.1101/2024.08.22.24312320

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