Article
Molecular Pathology of Prostate Cancer.
Clinics in laboratory medicine - 1 Jun 2024
Kulac Ibrahim, Roudier Martine P, Haffner Michael C
Abstract excerpt
Molecular profiling studies have shed new light on the complex biology of prostate cancer. Genomic studies have highlighted that structural rearrangements are among the most common recurrent alterations. In addition, both germline and somatic mutations in DNA repair genes are enriched in patients with advanced disease. Primary prostate cancer has long been known to be multifocal, but recent studies demonstrate...
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