High‐resolution genome‐wide copy‐number analysis suggests a monoclonal origin of multifocal prostate cancer

Abstract excerpt

Many human cancers present as multifocal lesions. Understanding the clonal origin of multifocal cancers is of both etiological and clinical importance. The molecular basis of multifocal prostate cancer has previously been explored using a limited number of isolated markers and, although independent origin is widely believed, the clonal origin of multifocal prostate cancer is still debatable. We attempted to...

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