Article

The protein phosphatase-2A subunit PR130 is linked to cytotoxic protein aggregate formation in mesenchymal pancreatic ductal adenocarcinoma cells

2023-09-05

Abstract excerpt

<h4>ABSTRACT</h4> Protein phosphatase-2A (PP2A) is a major source of cellular serine/threonine phosphatase activity. PP2A B-type subunits regulate the intracellular localization and the catalytic activity of PP2A-A/PP2A-C complexes towards individual proteins. There is limited knowledge on how PP2A B-type subunits regulate biologically important functions and if these subunits determine the growth and drug respon...

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Literature Corpus work: 515d586b-7a93-5030-b4c7-8c83d5b78a59
DOI: 10.1101/2023.09.03.556106

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