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Article

CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1

26 Jul 2023

Abstract excerpt

CCR4-NOT transcription complex subunit 4 (CNOT4) and RNA polymerase II-associated factor, homolog (Saccharomyces cerevisiae) (PAF1) are implicated in nonsmall cell lung cancer (NSCLC). However, the molecular mechanism of their interaction in NSCLC progression is unknown. The expression of PAF1 and CNOT4 in human NSCLC tissues was detected by quantitative polymerase chain reaction. A549 cells that stably expressed...

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PMID: 37493105
DOI: 10.1002/mc.23599

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