Article
HistoneDB 2.0: a histone database with variants--an integrated resource to explore histones and their variants.
Database : the journal of biological databases and curation - 1 Jan 2016
Draizen Eli J, Shaytan Alexey K, Mariño-Ramírez Leonardo, Talbert Paul B, Landsman David, Panchenko Anna R
Abstract excerpt
Compaction of DNA into chromatin is a characteristic feature of eukaryotic organisms. The core (H2A, H2B, H3, H4) and linker (H1) histone proteins are responsible for this compaction through the formation of nucleosomes and higher order chromatin aggregates. Moreover, histones are intricately involved in chromatin functioning and provide a means for genome dynamic regulation through specific histone variants and...
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