Article

Assessing the basal gene expression of cancer cell lines for in vitro transcriptomic toxicology screening

2023-07-29

Abstract excerpt

<h4>ABSTRACT</h4> In vitro toxicology has used immortalized cancer cell lines as model human systems for decades. However, these cell lines pose problems in designing toxicity testing programs as they inherently do not represent normal human biology. There is also a huge number of such cell lines to choose from, derived from human cancer cells from nearly every tissue. We explored the idea of using available basa...

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Literature Corpus work: f0737a30-7505-56b7-b38d-6d7947333a78
DOI: 10.1101/2023.07.26.550714

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