Article

Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis

2023-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Arl13b and Arl3 are ciliary GTPases implicated in human Joubert Syndrome, affecting ciliary membrane and axoneme organization. Although the mechanism of Arl13b as a guanine nucleotide exchange factor (GEF) of Arl3 and the function of Arl13b and Arl3 in ciliary membrane protein transport are well established, their role in axoneme biogenesis is unclear. In Trypanosoma brucei , TbArl13 acts as a...

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Literature Corpus work: 5e1bb3d0-c017-5cac-8fd5-e7ea66cbcdac
DOI: 10.1101/2023.04.12.536397

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