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Article

Investigating chromosomal radiosensitivity in inborn errors of immunity: insights from DNA repair disorders and beyond

2024-08-20

Abstract excerpt

<h4>ABSTRACT</h4> Human inborn errors of immunity (IEI) represent a diverse group of genetic disorders affecting the innate and/or adaptive immune system. Some IEI entities comprise defects in DNA repair factors, resulting in (severe) combined immunodeficiencies, bone marrow failure, predisposition to malignancies, and potentially result in radiosensitivity (RS). While other IEI subcategories such as common variab...

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Identifiers and source

Literature Corpus work
f02c107a-2373-51d7-a2fb-8df3a09716b8
DOI
10.1101/2024.08.14.24311337
Open publication

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Investigating chromosomal radiosensitivity in inborn errors of immunity: insights from DNA repair disorders and beyondDOI 10.1101/2024.08.14.24311337
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