Article
DNA replication-associated inborn errors of immunity.
The Journal of allergy and clinical immunology - 1 Feb 2023
Willemsen Mathijs, Staels Frederik, Gerbaux Margaux, Neumann Julika, Schrijvers Rik, Meyts Isabelle, Humblet-Baron Stephanie, Liston Adrian
Abstract excerpt
Inborn errors of immunity are a heterogeneous group of monogenic immunologic disorders caused by mutations in genes with critical roles in the development, maintenance, or function of the immune system. The genetic basis is frequently a mutation in a gene with restricted expression and/or function in immune cells, leading to an immune disorder. Several classes of inborn errors of immunity, however, result from...
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