Article

Epigenetic regulation of Leukocyte associated immunoglobulin-like receptors 1 and 2 by interferon signaling in macrophages and T cells

2023-08-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Inhibitory immune receptors are important for maintaining immune homeostasis. We recently identified epigenetic alterations in two members of this group, LAIR1 and LAIR2, in patients with inflammatory tissue damage and recurrent skin and soft tissue infections. We therefore hypothesized that the expression of LAIR1 and LAIR2 may be controlled by immune stimuli acting on disc...

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Literature Corpus work: efdb0305-5c16-5c31-afae-ef77d9dea4a0
DOI: 10.1101/2023.07.31.551385

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