Article

Linking T cell receptor sequence to transcriptional profiles with clonotype neighbor graph analysis (CoNGA)

2020-06-05

Abstract excerpt

Multi-modal single-cell technologies capable of simultaneously assaying gene expression and surface phenotype across large numbers of immune cells have described extensive heterogeneity within these complex populations, in healthy and diseased states. In the case of T cells, these technologies have made it possible to profile clonotype, defined by T cell receptor (TCR) sequence, and phenotype, as reflected in gene...

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Literature Corpus work: efcf98a5-a199-5531-8f5a-c599946bde75
DOI: 10.1101/2020.06.04.134536

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