Article

Single-cell immune profiling with TCR clonotype barcoding identifies biomarker signatures that predict response to immune checkpoint blockade

2021-04-14

Abstract excerpt

The identification of predictive biomarkers for patient treatment response is urgently needed to increase the probability of success of existing and novel experimental therapies. Single-cell profiling has provided novel biological insights into drug responses in the tumor microenvironment, but its potential for biomarker discovery has not been fully explored for therapeutic purposes. We describe a novel approach t...

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Literature Corpus work: 7c728c44-7e98-5c2f-a442-62a7fb925fb7
DOI: 10.1101/2021.04.13.439713

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