Article

T cell receptor-centric perspective to multimodal single-cell data analysis

2023-09-29

Abstract excerpt

The T-cell receptor (TCR) carries critical information regarding T-cell functionality. The TCR, despite its importance, is underutilized in single cell transcriptomics, with gene expression (GEx) features solely driving current analysis strategies. Here, we argue for a switch to a TCR-first approach, which would uncover unprecedented insights into T cell and TCR repertoire mechanics. To this end, we curated a larg...

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Literature Corpus work: e946d5dc-f2c1-52e1-8044-28780dbbbc8a
DOI: 10.1101/2023.09.27.559702

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