Article

Molecular basis of the urate transporter URAT1 inhibition by gout drugs

2024-09-12

Abstract excerpt

Hyperuricemia is a condition when uric acid, a waste product of purine metabolism, accumulates in the blood 1 . Untreated hyperuricemia can lead to crystal formation of monosodium urate in the joints, causing a painful inflammatory disease known as gout. These conditions are associated with many other diseases and affect a significant and increasing proportion of the population 2–4 . The human urate transporter...

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Literature Corpus work: efba9468-c2cb-5261-8562-7940d9088091
DOI: 10.1101/2024.09.11.612563

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