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Article

The in-silico evaluation of important GLUT9 residue for uric acid transport based on renal hypouricemia type 2.

Chemico-biological interactions - 1 Mar 2023

Cachau Raul, Shahsavari Shahin, Cho Sung Kweon

Abstract excerpt

Uric acid is the end product of purine metabolism. Uric acid transporters in the renal proximal tubule plays a key role in uric acid transport. Functional abnormalities in these transporters could lead to high or low levels of uric acid in the blood plasma, known as hyperuricemia and hypouricemia, respectively. GLUT9 has been reported as a key transporter for uric acid reuptake in renal proximal tubule. GLUT9...

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Share to Glucose Transport Proteins, Facilitative
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Organic Anion Transporters

Share to Renal Tubular Transport, Inborn Errors

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Identifiers

PMID: 36736875
DOI: 10.1016/j.cbi.2023.110378
PMCID: PMC10596759

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