Article

Mutations in the Fas Antigen in Patients With Multiple Myeloma

1997-12-01

Abstract excerpt

Abstract Programmed cell death, or apoptosis, is well documented as a physiological means of eliminating activated lymphocytes and maintaining immune homeostasis. Apoptosis has also been implicated in the targeting of tumor cells by cytotoxic T lymphocytes and natural killer cells. One of the two primary mechanisms used in cell-mediated cytotoxicity is the Fas/FasLigand system. Activated or transformed cells expre...

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Identifiers and source

Literature Corpus work: efb63330-9da2-51a6-87c9-cbff375aed06
DOI: 10.1182/blood.v90.11.4266

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