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Article

Analysis of FAS (CD95) gene mutations in higher-grade transformation of follicle center lymphoma.

Leukemia & lymphoma - 1 Aug 2003

Do Bao, Lossos Izidore S, Thorstenson Yvonne, Oefner Peter J, Levy Ronald

Abstract excerpt

The FAS antigen (CD95/APO-1) is suggested to be a tumor suppressor gene since mice and patients with congenital FAS mutations are prone to B cell lymphomas and somatic FAS mutations are described in hematological and solid tumors. Indeed, mutations of the FAS antigen have been found in 13% of multiple myelomas, 6% of follicle center lymphomas (FCL) and 21% of diffuse large B-cell lymphomas (DLBCL). To assess the...

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Source

Identifiers

PMID: 12952224
DOI: 10.1080/1042819031000090228

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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