Article

Comparison of the effects of oxidative and inflammatory stresses on rat chondrocyte senescence

2022-12-12

Abstract excerpt

Osteoarthritis (OA) is an age-related degenerative joint disease that causes progressive cartilage loss. Chondrocyte senescence is a fundamental mechanism that contributes to the imbalance of matrix homeostasis in OA by inducing senescence-associated secretory phenotype (SASP). Although OA chondrocytes are mainly exposed to oxidative and inflammatory stresses, the role of these individual stresses in chondrocyte s...

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Literature Corpus work: ef978d40-69a5-5bee-a120-c782c2b2167c
DOI: 10.21203/rs.3.rs-2344156/v1

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