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Cellular senescence in osteoarthritis pathology

26 Jan 2017

Abstract excerpt

Cellular senescence is a state of stable proliferation arrest of cells. The senescence pathway has many beneficial effects and is seen to be activated in damaged/stressed cells, as well as during embryonic development and wound healing. However, the persistence and accumulation of senescent cells in various tissues can also impair function and have been implicated in the pathogenesis of many age-related diseases....

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PMID: 28124466
DOI: 10.1111/acel.12562

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