Article
Guanine content of microRNAs is associated with their tumor suppressive and oncogenic roles in lung and breast cancers
2019-01-11
Abstract excerpt
<h4>Background</h4> microRNAs (miRNAs, miRs) are small noncoding RNAs that negatively regulate gene expression at the post-transcriptional level and fine-tune gene functions. A global repression of miRNAs expression in different types of human tumors, after exposure to cigarette-smoke, or to the hormone estrogen, have been shown to be associated with guanine (G) enrichment in the terminal loops (TLs) of their pre...
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Identifiers and source
- Literature Corpus work
- 36b2bcb0-ac1b-5f58-ae9d-e3f996700188
- DOI
- 10.1101/518472
