Article

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

2022-07-12

Abstract excerpt

Effective humoral immune responses require well-orchestrated cellular interactions between B and T follicular helper (Tfh) cells. Whether this interaction is impaired and associated with COVID-19 disease severity is unknown. Here, longitudinal acute and convalescent blood samples from 49 COVID-19 patients across mild to severe disease were analysed. We found that during acute infection activated and SARS-CoV-2-spe...

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Literature Corpus work: 6df43d54-a12d-553d-b7d1-61473ebf5cbb
DOI: 10.1101/2022.07.12.22277549

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