Article

Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors

2018-05-22

Abstract excerpt

We have previously designed a library of lentiviral vectors to generate somatic-transgenic rodents to monitor signalling pathways in diseased organs using whole-body bioluminescence imaging, in conscious, freely moving rodents. We have now expanded this technology to adeno-associated viral vectors. We first explored bio-distribution by assessing GFP expression after neonatal intravenous delivery of AAV8. We observ...

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Literature Corpus work: eeea73b7-154a-540b-bff7-438172368dd5
DOI: 10.1101/328310

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