Article

Swine reporter model for preclinical evaluation and characterization of gene delivery vectors

2025-06-14

Abstract excerpt

<h4>ABSTRACT</h4> Delivery of gene therapy vectors targeted to any somatic cell remains a key barrier for the development of genetic medicines. While rodent models provide insights into vector biodistribution and cellular tropism, their anatomical and physiological differences from humans limit their translational potential and studies in large animal models are often required. In this study, we developed a swine...

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Literature Corpus work: dcd79dd4-03b3-56fe-925e-5b75b6847e6b
DOI: 10.1101/2025.06.13.659546

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