Article

Non-invasive somatotransgenic bioimaging in living animals

2020-10-09

Abstract excerpt

Bioluminescence imaging enables noninvasive quantification of luciferase reporter gene expression in transgenic tissues of living rodents. Luciferase transgene expression can be regulated by endogenous gene promoters after targeted knock-in of the reporter gene, usually within the first intron of the gene. Even using CRISPR/Cas9 mediated genome editing this can be a time consuming and costly process. The generatio...

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Literature Corpus work: 6a2a5589-e909-5fd2-8ba9-d2deccdb673e
DOI: 10.12688/f1000research.25274.1

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