Article

Targeted gene transfer into developmentally defined cell populations of the primate brain

2025-04-17

Abstract excerpt

The primate brain possesses unique physiological and developmental features whose systematic investigation is hampered by a paucity of transgenic germline models and tools. Here, we present a minimally invasive method to introduce transgenes widely across the primate cerebral cortex using ultrasound-guided fetal intracerebroventricular viral injections (FIVI). This technique enables rapid-onset and long-lasting tr...

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Literature Corpus work: b33b694b-2aea-522b-bfbb-09772026d5ea
DOI: 10.1101/2025.04.11.648413

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